BDBM192668 2-phenyl-5-(4-nitrophenyl)-1,3,4-oxadiazole (2k)

SMILES [O-][N+](=O)c1ccc(cc1)-c1nnc(o1)-c1ccccc1

InChI Key InChIKey=CBJSXHPYQDUZOO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 192668   

TargetCathepsin L(Goat)
Kurukshetra University

LigandPNGBDBM192668(2-phenyl-5-(4-nitrophenyl)-1,3,4-oxadiazole (2k))
Affinity DataKi:  47.3nM ΔG°:  -10.4kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2016
Entry Details Article
PubMed
TargetCathepsin B(Goat)
Kurukshetra University

LigandPNGBDBM192668(2-phenyl-5-(4-nitrophenyl)-1,3,4-oxadiazole (2k))
Affinity DataKi:  664nM ΔG°:  -8.76kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2016
Entry Details Article
PubMed
TargetCathepsin H(Goat)
Kurukshetra University

LigandPNGBDBM192668(2-phenyl-5-(4-nitrophenyl)-1,3,4-oxadiazole (2k))
Affinity DataKi:  4.96E+3nM ΔG°:  -7.52kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2016
Entry Details Article
PubMed