BDBM192667 2-phenyl-5-(2-nitrophenyl)-1,3,4-oxadiazole (2i)

SMILES [O-][N+](=O)c1ccccc1-c1nnc(o1)-c1ccccc1

InChI Key InChIKey=LIJMRRGETTVLFW-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 192667   

TargetCathepsin L(Goat)
Kurukshetra University

LigandPNGBDBM192667(2-phenyl-5-(2-nitrophenyl)-1,3,4-oxadiazole (2i))
Affinity DataKi:  57nM ΔG°:  -10.3kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2016
Entry Details Article
PubMed
TargetCathepsin B(Goat)
Kurukshetra University

LigandPNGBDBM192667(2-phenyl-5-(2-nitrophenyl)-1,3,4-oxadiazole (2i))
Affinity DataKi:  790nM ΔG°:  -8.65kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2016
Entry Details Article
PubMed
TargetCathepsin H(Goat)
Kurukshetra University

LigandPNGBDBM192667(2-phenyl-5-(2-nitrophenyl)-1,3,4-oxadiazole (2i))
Affinity DataKi:  6.69E+3nM ΔG°:  -7.34kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2016
Entry Details Article
PubMed