BDBM192317 US9187459, 2

SMILES CN(C)C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCC1C2COCC12

InChI Key InChIKey=YFQGFLOTVWXVMG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 192317   

TargetEpidermal growth factor receptor(Human)
Newgen Therapeutics

US Patent
LigandPNGBDBM192317(US9187459, 2)
Affinity DataIC50: 0.130nMT: 2°CAssay Description:1) The compound is dissolved in DMSO to prepare a 10 mM solution, and was diluted to 100 micoM with water. When used for IC50 measurement, series dil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Newgen Therapeutics

US Patent
LigandPNGBDBM192317(US9187459, 2)
Affinity DataIC50: 6nMT: 2°CAssay Description:1) The compound is dissolved in DMSO to prepare a 10 mM solution, and was diluted to 100 micoM with water. When used for IC50 measurement, series dil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
Go to US Patent