BDBM192186 US10526329, Compound 83::US11072611, Compound 83::US9670204, 83 4-(3,4-difluorophenyl)-N-(2-ethyl-6-(1-(methylsulfonyl)piperidin-4-yl)imidazo[1,2-a]pyridin-3-yl)-N-methylthiazol-2-amine
SMILES CCc1nc2ccc(cn2c1N(C)c1nc(cs1)-c1ccc(F)c(F)c1)C1CCN(CC1)S(C)(=O)=O
InChI Key InChIKey=YIHHFWPRAIRVHE-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 192186
Affinity DataIC50: 1.00E+3nMpH: 8.5 T: 2°CAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate. 5 μL of a di...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:TABLE V: 5 μL of a dilution series of compound, starting from 20 μM highest concentration, 1/5 dilution, is added to the wells. hENPP2 is u...More data for this Ligand-Target Pair