BDBM192130 US9187437, 26

SMILES COc1ccc(OC)c(c1)-c1noc(CCC2(CCCCC2)c2ccccc2)n1

InChI Key InChIKey=IVHFUHJLMRGHCY-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 192130   

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM192130(US9187437, 26)
Affinity DataIC50: 8.10nMpH: 7.5 T: 2°CAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1x108 cells/pellet) were suspended in buffer containing 20 mM HEPES, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
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TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM192130(US9187437, 26)
Affinity DataEC50:  4.90E+3nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Ga1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
Go to US Patent

TargetSphingosine 1-phosphate receptor 3(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM192130(US9187437, 26)
Affinity DataEC50:  1.60E+4nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Ga1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
Go to US Patent