BDBM191876 US9187429, 1

SMILES NC1CCCc2c1cncc2-c1ccc(cc1)C#N

InChI Key InChIKey=KAIKMBLZNQPQSC-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 191876   

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM191876(US9187429, 1)
Affinity DataEC50:  173nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM191876(US9187429, 1)
Affinity DataEC50:  42nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM191876(US9187429, 1)
Affinity DataIC50: 42nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed