BDBM191779 US9187428, 7

SMILES CNC(=O)c1cc(CSc2nc(N)c(C#N)c(-c3ccc(OCC(C)(C)O)cc3)c2C#N)ccn1

InChI Key InChIKey=XQOOPCOOQAMMQP-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 191779   

TargetAdenosine receptor A1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM191779(US9187428, 7)
Affinity DataEC50:  0.100nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM191779(US9187428, 7)
Affinity DataEC50:  460nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A2b(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM191779(US9187428, 7)
Affinity DataEC50:  32nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent