BDBM19155 (6R,9S,12R,16R)-16-[(1E)-4-(acetylsulfanyl)but-1-en-1-yl]-9,12-dimethyl-6-(propan-2-yl)-1-oxa-4,7,10,13-tetraazacyclohexadecane-2,5,8,11,14-pentone::FK228 Analogue, 15b

SMILES CC(C)[C@H]1NC(=O)[C@H](C)NC(=O)[C@@H](C)NC(=O)C[C@@H](OC(=O)CNC1=O)\C=C\CCSC(C)=O

InChI Key InChIKey=DSOSPBZVBBLRHS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19155   

TargetHistone deacetylase 6(Mouse)
University of Southampton

LigandPNGBDBM19155((6R,9S,12R,16R)-16-[(1E)-4-(acetylsulfanyl)but-1-e...)
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2007
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Southampton

LigandPNGBDBM19155((6R,9S,12R,16R)-16-[(1E)-4-(acetylsulfanyl)but-1-e...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2007
Entry Details Article
PubMed