BDBM191489 US9181272, 259

SMILES CC(C#N)c1cncc(c1)-c1cnc2N(CCCc2c1)C(N)=O

InChI Key InChIKey=AFDUFMMORKZZEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 191489   

TargetCytochrome P450 family 11 subfamily B member 2(Green monkey)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM191489(US9181272, 259)
Affinity DataIC50: 4.40nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2016
Entry Details
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