BDBM19148 benzyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulfanylhexyl]carbamate::thiolate analogue, 40a

SMILES SCCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)NC1CCCC1

InChI Key InChIKey=TYBDKDNZVXAQGQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19148   

TargetHistone deacetylase 6(Mouse)
Nagoya City University

LigandPNGBDBM19148(benzyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulfanyl...)
Affinity DataIC50: 78nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2007
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Nagoya City University

LigandPNGBDBM19148(benzyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulfanyl...)
Affinity DataIC50: 130nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2007
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Nagoya City University

LigandPNGBDBM19148(benzyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulfanyl...)
Affinity DataIC50: 130nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2007
Entry Details Article
PubMed