BDBM19145 (2S)-2-[(tert-butylcarbamothioyl)amino]-N-cyclopentyl-7-sulfanylheptanamide::thiolate analogue, 36a

SMILES CC(C)(C)NC(=S)N[C@@H](CCCCCS)C(=O)NC1CCCC1

InChI Key InChIKey=VXMHHEQJZJBMRW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19145   

TargetHistone deacetylase 6(Mouse)
Nagoya City University

LigandPNGBDBM19145((2S)-2-[(tert-butylcarbamothioyl)amino]-N-cyclopen...)
Affinity DataIC50: 170nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2007
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Nagoya City University

LigandPNGBDBM19145((2S)-2-[(tert-butylcarbamothioyl)amino]-N-cyclopen...)
Affinity DataIC50: 220nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2007
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Nagoya City University

LigandPNGBDBM19145((2S)-2-[(tert-butylcarbamothioyl)amino]-N-cyclopen...)
Affinity DataIC50: 400nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2007
Entry Details Article
PubMed