BDBM19132 tert-butyl N-[(1S)-1-[(3-phenylphenyl)carbamoyl]-6-sulfanylhexyl]carbamate::thiolate analogue, 13a

SMILES CC(C)(C)OC(=O)N[C@@H](CCCCCS)C(=O)Nc1cccc(c1)-c1ccccc1

InChI Key InChIKey=JITODBYUQIXPEO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19132   

TargetHistone deacetylase 6(Mouse)
Nagoya City University

LigandPNGBDBM19132(tert-butyl N-[(1S)-1-[(3-phenylphenyl)carbamoyl]-6...)
Affinity DataIC50: 54nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2007
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Nagoya City University

LigandPNGBDBM19132(tert-butyl N-[(1S)-1-[(3-phenylphenyl)carbamoyl]-6...)
Affinity DataIC50: 62nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2007
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Nagoya City University

LigandPNGBDBM19132(tert-butyl N-[(1S)-1-[(3-phenylphenyl)carbamoyl]-6...)
Affinity DataIC50: 38nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2007
Entry Details Article
PubMed