BDBM191282 US9181272, 52

SMILES Cn1c(cc2ccccc12)-c1cncc(-c2cnc3N(CCCc3c2)C(N)=O)c1C#N

InChI Key InChIKey=FXICMQDSZFNZSW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 191282   

TargetCytochrome P450 family 11 subfamily B member 2(Green monkey)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM191282(US9181272, 52)
Affinity DataIC50: 5.70nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2016
Entry Details
Go to US Patent