BDBM19126 (1R,3R,6R,7S,8R,10S,11S,14R,15R,20S)-18-[(2S)-butan-2-yl]-7-[(1S)-1-(dimethylamino)ethyl]-8-hydroxy-6,10,15-trimethyl-17,19-diazahexacyclo[12.8.0.0^{1,3}.0^{3,11}.0^{6,10}.0^{15,20}]docos-18-en-4-one::pyrimidine, 26b

SMILES [H][C@@]12CC[C@]3([H])[C@]4(C[C@@]14C(=O)C[C@]1(C)[C@@H]([C@H](C)N(C)C)[C@H](O)C[C@@]21C)CC[C@@H]1N=C(NC[C@@]31C)[C@@H](C)CC

InChI Key InChIKey=VWLHALGORHXQJY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 19126   

TargetAcetylcholinesterase(Electric eel)
Cnrs

LigandPNGBDBM19126((1R,3R,6R,7S,8R,10S,11S,14R,15R,20S)-18-[(2S)-buta...)
Affinity DataIC50: 14nMAssay Description:Inhibition of AChE activity was determined by the spectroscopic method of Ellman using acetylthiocholine iodide as substrate, in 96-well microtiter p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2007
Entry Details Article
PubMed
TargetAcetylcholinesterase(Pacific electric ray)
Cnrs

LigandPNGBDBM19126((1R,3R,6R,7S,8R,10S,11S,14R,15R,20S)-18-[(2S)-buta...)
Affinity DataIC50: 2nMAssay Description:Inhibition of AChE activity was determined by the spectroscopic method of Ellman using acetylthiocholine iodide as substrate, in 96-well microtiter p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2007
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Cnrs

LigandPNGBDBM19126((1R,3R,6R,7S,8R,10S,11S,14R,15R,20S)-18-[(2S)-buta...)
Affinity DataIC50: 6.49E+3nMAssay Description:Inhibition of AChE activity was determined by the spectroscopic method of Ellman using acetylthiocholine iodide as substrate, in 96-well microtiter p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2007
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Cnrs

LigandPNGBDBM19126((1R,3R,6R,7S,8R,10S,11S,14R,15R,20S)-18-[(2S)-buta...)
Affinity DataIC50: 4.37E+3nMAssay Description:Inhibition of AChE activity was determined by the spectroscopic method of Ellman using acetylthiocholine iodide as substrate, in 96-well microtiter p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2007
Entry Details Article
PubMed