BDBM19122 (3R,6R,7S,8R,10S,11R,14R,15S,20S)-8-hydroxy-6,10,15-trimethyl-7-[(1S)-1-(methylamino)ethyl]-18-(propan-2-yl)-17-oxa-19-azapentacyclo[12.8.0.0^{3,11}.0^{6,10}.0^{15,20}]docosa-1(22),18-dien-4-one::oxazine, 19

SMILES [H][C@@]12CC3=CC[C@@H]4N=C(OC[C@@]4(C)[C@]3([H])CC[C@@]1([H])[C@]1(C)C[C@@H](O)[C@H]([C@H](C)NC)[C@@]1(C)CC2=O)C(C)C

InChI Key InChIKey=UQAHSQZJTMTZHV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 19122   

TargetAcetylcholinesterase(Electric eel)
Cnrs

LigandPNGBDBM19122((3R,6R,7S,8R,10S,11R,14R,15S,20S)-8-hydroxy-6,10,1...)
Affinity DataIC50: 106nMAssay Description:Inhibition of AChE activity was determined by the spectroscopic method of Ellman using acetylthiocholine iodide as substrate, in 96-well microtiter p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2007
Entry Details Article
PubMed
TargetAcetylcholinesterase(Pacific electric ray)
Cnrs

LigandPNGBDBM19122((3R,6R,7S,8R,10S,11R,14R,15S,20S)-8-hydroxy-6,10,1...)
Affinity DataIC50: 485nMAssay Description:Inhibition of AChE activity was determined by the spectroscopic method of Ellman using acetylthiocholine iodide as substrate, in 96-well microtiter p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2007
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Cnrs

LigandPNGBDBM19122((3R,6R,7S,8R,10S,11R,14R,15S,20S)-8-hydroxy-6,10,1...)
Affinity DataIC50: 2.23E+3nMAssay Description:Inhibition of AChE activity was determined by the spectroscopic method of Ellman using acetylthiocholine iodide as substrate, in 96-well microtiter p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2007
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Cnrs

LigandPNGBDBM19122((3R,6R,7S,8R,10S,11R,14R,15S,20S)-8-hydroxy-6,10,1...)
Affinity DataIC50: 517nMAssay Description:Inhibition of AChE activity was determined by the spectroscopic method of Ellman using acetylthiocholine iodide as substrate, in 96-well microtiter p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2007
Entry Details Article
PubMed