BDBM1912 1-[2-(2,5-dimethoxyphenyl)ethyl]-3-1,3-thiazol-2-ylthiourea::N-(2-(2,5-Dimethoxyphenethyl))-N -(2-thiazolyl)thiourea::PETT Analog 19

SMILES COc1ccc(OC)c(CCNC(=S)Nc2nccs2)c1

InChI Key InChIKey=KDZKARFVKQOTDJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1912   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM1912(N-(2-(2,5-Dimethoxyphenethyl))-N -(2-thiazolyl)thi...)
Affinity DataIC50: 200nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2004
Entry Details Article
PubMed