BDBM19114 (3R,6R,7S,8R,10S,11R,14R,15S,20S)-18-cyclohexyl-7-[(1S)-1-(dimethylamino)ethyl]-8-hydroxy-6,10,15-trimethyl-17-oxa-19-azapentacyclo[12.8.0.0^{3,11}.0^{6,10}.0^{15,20}]docosa-1(22),18-dien-4-one::oxazine, 9h

SMILES [H][C@@]12CC3=CC[C@@H]4N=C(OC[C@@]4(C)[C@]3([H])CC[C@@]1([H])[C@]1(C)C[C@@H](O)[C@H]([C@H](C)N(C)C)[C@@]1(C)CC2=O)C1CCCCC1

InChI Key InChIKey=KBJVXAZGEOCZQO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19114   

TargetAcetylcholinesterase(Electric eel)
Cnrs

LigandPNGBDBM19114((3R,6R,7S,8R,10S,11R,14R,15S,20S)-18-cyclohexyl-7-...)
Affinity DataIC50: 400nMpH: 8.0 T: 2°CAssay Description:Inhibition of AChE activity was determined by the spectroscopic method of Ellman using acetylthiocholine iodide as substrate, in 96-well microtiter p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2007
Entry Details Article
PubMed
TargetCholinesterase(Human)
Cnrs

LigandPNGBDBM19114((3R,6R,7S,8R,10S,11R,14R,15S,20S)-18-cyclohexyl-7-...)
Affinity DataIC50: 375nMpH: 8.0 T: 2°CAssay Description:Inhibition of BuChE activity was determined by the spectroscopic method of Ellman using butyrylthiocholine iodide as substrate, in 96-well microtiter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2007
Entry Details Article
PubMed