BDBM190980 US10077266, Example 93::US9181249, 93::US9708313, 93

SMILES COc1ccc(OC2CCN(CC2)c2nc3CN(CCc3nc2NC2CCC2)C(=O)N(C)C)c(F)c1

InChI Key InChIKey=MBEGIEVLFABLED-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 190980   

TargetG-protein coupled receptor 6(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM190980(US9708313, 93 | US9181249, 93 | US10077266, Exampl...)
Affinity DataIC50: 0.0138nMT: 2°CAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2016
Entry Details
Go to US Patent

TargetG-protein coupled receptor 6(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM190980(US9708313, 93 | US9181249, 93 | US10077266, Exampl...)
Affinity DataIC50: 1.38E+4nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
Go to US Patent

TargetG-protein coupled receptor 6(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM190980(US9708313, 93 | US9181249, 93 | US10077266, Exampl...)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of cAMP Activity of GPR6 In Vitro AssayThis cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent