BDBM190968 US10077266, Example 81::US9181249, 81::US9708313, 81

SMILES O=C1NC[C@@H](C(=O)NC(c2ccc(Cl)cc2)c2ccc(Cl)c(C(F)(F)F)n2)O1

InChI Key InChIKey=OLWFSHRVTXHOAB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 190968   

TargetSodium channel protein type 8 subunit alpha(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 190968BDBM190968((S)—N—((R)-(5-chloro-6-(trifluoromethyl)pyridin-2-...)
Affinity DataIC50: 0.600nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2026
Entry Details
US Patent