BDBM190958 US10077266, Example 71::US9181249, 71::US9708313, 71

SMILES CC(C)Nc1nc2CCN(Cc2nc1N1CCC(CC1)C(F)c1ccc(F)cc1F)C(C)=O

InChI Key InChIKey=HUXMBOZHWUYKBH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 190958   

TargetG-protein coupled receptor 6(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM190958(US9708313, 71 | US9181249, 71 | US10077266, Exampl...)
Affinity DataIC50: 0.00850nMT: 2°CAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2016
Entry Details
Go to US Patent

TargetG-protein coupled receptor 6(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM190958(US9708313, 71 | US9181249, 71 | US10077266, Exampl...)
Affinity DataIC50: 8.50E+3nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
Go to US Patent

TargetG-protein coupled receptor 6(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM190958(US9708313, 71 | US9181249, 71 | US10077266, Exampl...)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of cAMP Activity of GPR6 In Vitro AssayThis cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent