BDBM190677 US9181233, 49

SMILES COc1cccc(CCc2nnc(s2)-c2ccc3[nH]cnc3c2)c1OC

InChI Key InChIKey=PGOIBMREWDPPGV-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 190677   

TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Probiodrug

US Patent
LigandPNGBDBM190677(US9181233, 49)
Affinity DataKi:  90nM ΔG°:  -9.77kcal/mole IC50: 360nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2016
Entry Details
Go to US Patent