BDBM190591 US9181219, 2-[(3-chloropyridin-2-yl)sulfanyl]-1-(8-methoxy-1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one

SMILES COc1cccc2CCCN(C(=O)CSc3ncccc3Cl)c12

InChI Key InChIKey=RCQANPHBEVONMT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 190591   

LigandPNGBDBM190591(US9181219, 2-[(3-chloropyridin-2-yl)sulfanyl]-1-(8...)
Affinity DataIC50: 500nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

LigandPNGBDBM190591(US9181219, 2-[(3-chloropyridin-2-yl)sulfanyl]-1-(8...)
Affinity DataIC50: 500nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent