BDBM190589 US9181219, 2-{[2-(8-methyl-1,2,3,4-tetrahydroquinolin-1-yl)-2-oxoethyl]sulfanyl}pyridine-4-carbonitrile

SMILES Cc1cccc2CCCN(C(=O)CSc3cc(ccn3)C#N)c12

InChI Key InChIKey=RJKDMFFWGYMYLZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 190589   

LigandPNGBDBM190589(US9181219, 2-{[2-(8-methyl-1,2,3,4-tetrahydroquino...)
Affinity DataIC50: 1.00E+4nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

LigandPNGBDBM190589(US9181219, 2-{[2-(8-methyl-1,2,3,4-tetrahydroquino...)
Affinity DataIC50: 1.00E+4nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent