BDBM190588 US9181219, 2-[(3,5-dichloropyridin-2-yl)sulfanyl]-1-(8-methyl-1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one

SMILES Cc1cccc2CCCN(C(=O)CSc3ncc(Cl)cc3Cl)c12

InChI Key InChIKey=FLTBYMGWJOPCBI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 190588   

LigandPNGBDBM190588(US9181219, 2-[(3,5-dichloropyridin-2-yl)sulfanyl]-...)
Affinity DataIC50: 200nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

LigandPNGBDBM190588(US9181219, 2-[(3,5-dichloropyridin-2-yl)sulfanyl]-...)
Affinity DataIC50: 200nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent