BDBM190587 US9181219, methyl 5-chloro-6-{[2-(8-methyl-1,2,3,4-tetrahydroquinolin-1-yl)-2-oxoethyl]sulfanyl}pyridine-3-carboxylate

SMILES COC(=O)c1cnc(SCC(=O)N2CCCc3cccc(C)c23)c(Cl)c1

InChI Key InChIKey=GHXGNKHZWJMXFL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 190587   

LigandPNGBDBM190587(US9181219, methyl 5-chloro-6-{[2-(8-methyl-1,2,3,4...)
Affinity DataIC50: 5.00E+3nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

LigandPNGBDBM190587(US9181219, methyl 5-chloro-6-{[2-(8-methyl-1,2,3,4...)
Affinity DataIC50: 5.00E+3nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent