BDBM190578 US9181219, 16

SMILES Cc1cccc2CCCN(C(=O)CSc3ccc(Cl)cn3)c12

InChI Key InChIKey=AADFPUIVOUZLOS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 190578   

LigandPNGBDBM190578(US9181219, 16)
Affinity DataIC50: 500nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

LigandPNGBDBM190578(US9181219, 16)
Affinity DataIC50: 500nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 2 subunit alpha(Human)
Hydra Biosciences

US Patent
LigandPNGBDBM190578(US9181219, 16)
Affinity DataIC50: 3.00E+4nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Hydra Biosciences

US Patent
LigandPNGBDBM190578(US9181219, 16)
Affinity DataIC50: 5.00E+3nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent