BDBM19046 N-(1-{2-[(dimethylamino)methyl]phenyl}piperidin-4-yl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide::Pyrazole-based inhibitor containing N-arylpiperidiny, 11b

SMILES COc1ccc(cc1)-n1nc(cc1C(=O)NC1CCN(CC1)c1ccccc1CN(C)C)C(F)(F)F

InChI Key InChIKey=HGTRHZWAYWVDSC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19046   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM19046(N-(1-{2-[(dimethylamino)methyl]phenyl}piperidin-4-...)
Affinity DataKi:  8.80nM ΔG°:  -10.9kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2007
Entry Details Article
PubMed