BDBM19014 6-(4-aminophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-7-one::trifluoromethylpyrazole analogue, 34

SMILES COc1ccc(cc1)-n1nc(c2CCN(C(=O)c12)c1ccc(N)cc1)C(F)(F)F

InChI Key InChIKey=OGVWKHPUKXDHAB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19014   

TargetCoagulation factor X(Human)
Rheinische Friedrich-Wilhelms-Universita£T

Curated by ChEMBL
LigandPNGBDBM19014(6-(4-aminophenyl)-1-(4-methoxyphenyl)-3-(trifluoro...)
Affinity DataKi:  1.58E+3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Rheinische Friedrich-Wilhelms-Universita£T

Curated by ChEMBL
LigandPNGBDBM19014(6-(4-aminophenyl)-1-(4-methoxyphenyl)-3-(trifluoro...)
Affinity DataKi:  1.60E+3nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb

LigandPNGBDBM19014(6-(4-aminophenyl)-1-(4-methoxyphenyl)-3-(trifluoro...)
Affinity DataKi: >6.30E+3nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2007
Entry Details Article
PubMed