BDBM189816 US9174997, 20

SMILES CC1=C([N+]#[C-])[C@H](N(C(=O)N2CCN(CCO)CC2)C(=O)N1c1cccc(c1)C(F)(F)F)c1ccc(cc1S(C)(=O)=O)C#N

InChI Key InChIKey=VDNUSPMQNMMZPW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 189816   

TargetNeutrophil elastase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM189816(US9174997, 20)
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
Go to US Patent