BDBM18947 2-{4-[3-(benzylcarbamoyl)-4-hydroxyphenoxy]-3,5-dibromophenyl}acetic acid::4-hydroxy thyromimetic, 15b

SMILES OC(=O)Cc1cc(Br)c(Oc2ccc(O)c(c2)C(=O)NCc2ccccc2)c(Br)c1

InChI Key InChIKey=BDZRTRUPSHKGPB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 18947   

TargetThyroid hormone receptor alpha(Human)
Bristol-Myers Squibb

LigandPNGBDBM18947(2-{4-[3-(benzylcarbamoyl)-4-hydroxyphenoxy]-3,5-di...)
Affinity DataIC50: 84nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18947(2-{4-[3-(benzylcarbamoyl)-4-hydroxyphenoxy]-3,5-di...)
Affinity DataIC50: 4.20nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM18947(2-{4-[3-(benzylcarbamoyl)-4-hydroxyphenoxy]-3,5-di...)
Affinity DataIC50: 4.17nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Bristol-Myers Squibb

LigandPNGBDBM18947(2-{4-[3-(benzylcarbamoyl)-4-hydroxyphenoxy]-3,5-di...)
Affinity DataIC50: 85.1nMAssay Description:Inhibition of thyroid hormone receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed