BDBM189410 US9174969, CDL 4340-0580

SMILES CCOc1ccc(NC(=O)CN2C(=O)\C(=C3/SC(=S)C(CCS([O-])(=O)=O)C3=O)c3ccccc23)cc1

InChI Key InChIKey=TZPXYKJBCGWAPY-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 189410   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
University of South Florida

US Patent
LigandPNGBDBM189410(US9174969, CDL 4340-0580)
Affinity DataIC50: 2.20E+3nMAssay Description:IC50 values for indoline Shp2 inhibitors of the present invention, as determined by in vitro phosphotyrosine phosphatase activity (DiFMUP) assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent