BDBM189341 STOCK4S-60534 (6)

SMILES CCOc1ccc(cc1)N1CC(O)Cn2c1nc1n(C)c(=O)n(CC(=O)OCc3ccccc3)c(=O)c21

InChI Key InChIKey=KQLREHFTDRTJCM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 189341   

TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM189341(STOCK4S-60534 (6))
Affinity DataIC50: 2.85E+4nMpH: 8.1 T: 2°CAssay Description:RNA-dependent DNA polymerase (RDDP) activity was measured as described[J. Microbiol. 2015, 53:288-293] in Tris HCl buffer (25 mL, 60 mm, pH 8.1) cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2016
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM189341(STOCK4S-60534 (6))
Affinity DataIC50: 3.30E+4nMpH: 7.8 T: 2°CAssay Description:HIV RT-associated RNase H activity was measured as previously described.[J. Med. Chem. 2014, 57:3223-3234] Briefly, the reaction mixture comprised Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2016
Entry Details Article
PubMed