BDBM189329 (+)-(1-Acetyl-4-methyl-4-phenyl-1,2,3,4-tetrahydro-quinolin-6-yl)-carbamic acid 3-chloro-4-fluoro-benzyl ester (Compound C)::US9174940, Compound C

SMILES CC(=O)N1CCC(C)(c2ccccc2)c2cc(NC(=O)OCc3ccc(F)c(Cl)c3)ccc12

InChI Key InChIKey=IRWJUAWYXLTKDV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 189329   

TargetThyrotropin subunit beta(Bovine)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM189329(US9174940, Compound C | (+)-(1-Acetyl-4-methyl-4-p...)
Affinity DataIC50: 192nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM189329(US9174940, Compound C | (+)-(1-Acetyl-4-methyl-4-p...)
Affinity DataIC50: 47nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent