BDBM18871 2-(1-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy]phenyl}acetamido)acetic acid::N-acylated-alpha-amino acid derivative, 3a

SMILES CC(C)c1cc(Oc2c(Br)cc(CC(=O)NCC(O)=O)cc2Br)ccc1O

InChI Key InChIKey=BNNHEVBGBFFKOC-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18871   

TargetThyroid hormone receptor alpha(Human)
Karo Bio

LigandPNGBDBM18871(2-(1-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phen...)
Affinity DataIC50: 26nM EC50:  103nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

LigandPNGBDBM18871(2-(1-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phen...)
Affinity DataIC50: 2.70nM EC50:  42nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2007
Entry Details Article
PubMed