BDBM187391 US9169243, 39::US9908875, 39

SMILES C[C@H](n1cnnc1-c1nc(NC(=O)c2cc(c(cn2)N2CCN3C(COC3=O)C2)-n2cnc(c2)C2CC2)cs1)C(F)(F)F

InChI Key InChIKey=FUIPXUTXHGPFCR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 187391   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Gilead Sciences

US Patent
LigandPNGBDBM187391(US9169243, 39 | US9908875, 39)
Affinity DataIC50: 2.30nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection. This is a competitive, time...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Gilead Sciences

US Patent
LigandPNGBDBM187391(US9169243, 39 | US9908875, 39)
Affinity DataIC50: 2.30nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection. This is a competitive, time...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
Go to US Patent