BDBM18721 6-(5-fluoro-2-methoxyphenyl)-2,2-dimethyl-4-{[(2-phenylethyl)sulfanyl]methyl}-1,2-dihydroquinoline::dihydroquinoline compound, 44::dihydroquinoline-based ligand, 37

SMILES COc1ccc(F)cc1-c1ccc2NC(C)(C)C=C(CSCCc3ccccc3)c2c1

InChI Key InChIKey=VRGIPALWMYWNEK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 18721   

TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18721(dihydroquinoline-based ligand, 37 | 6-(5-fluoro-2-...)
Affinity DataIC50: 84nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2007
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18721(dihydroquinoline-based ligand, 37 | 6-(5-fluoro-2-...)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2007
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18721(dihydroquinoline-based ligand, 37 | 6-(5-fluoro-2-...)
Affinity DataIC50: 84nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2007
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18721(dihydroquinoline-based ligand, 37 | 6-(5-fluoro-2-...)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2007
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18721(dihydroquinoline-based ligand, 37 | 6-(5-fluoro-2-...)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2007
Entry Details Article
PubMed