BDBM187206 US9670181, 82 1-ethyl-4-((2-(ethylamino)-7-fluoro-6-methoxyquinolin-3-yl)methyl)-6,7-dimethoxyisoquinolin-3-ol

SMILES CCNc1nc2cc(F)c(OC)cc2cc1Cc1c(O)nc(CC)c2cc(OC)c(OC)cc12

InChI Key InChIKey=MNSIIAVQCFPATP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 187206   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Allergan

US Patent

LigandBDBM187206(US9670181, 82 1-ethyl-4-((2-(ethylamino)-7-fluoro-...)Copy SMILESCopy InChI

Affinity DataIC50: 1.40nMpH: 7.4 T: 2°CAssay Description:The PDE assay is based on the homogenous time-resolved fluorescence resonance energy transfer (TR-FRET) technology (LANCE from Perkin Elmer). This co...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/19/2018
Entry Details
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