BDBM187197 US9670181, 73 N-(2-((3-((3-hydroxy-6,7-dimethoxy-1-methylisoquinolin-4-yl)methyl)-6-methoxyquinolin-2-yl)amino)ethyl)acetamide

SMILES COc1ccc2nc(NCCNC(C)=O)c(Cc3c(O)nc(C)c4cc(OC)c(OC)cc34)cc2c1

InChI Key InChIKey=AGIISHUEHBCLLI-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 187197   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Allergan

US Patent

LigandBDBM187197(US9670181, 73 N-(2-((3-((3-hydroxy-6,7-dimethoxy-1...)Copy SMILESCopy InChI

Affinity DataIC50: 2.70nMpH: 7.4 T: 2°CAssay Description:The PDE assay is based on the homogenous time-resolved fluorescence resonance energy transfer (TR-FRET) technology (LANCE from Perkin Elmer). This co...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/19/2018
Entry Details
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