BDBM187182 US9670181, 61 1-ethyl-6,7-dimethoxy-4-((6-(methylamino)-[1,3]dioxolo[4,5-g]quinolin-7-yl)methyl)isoquinolin-3-ol

SMILES CCc1nc(O)c(Cc2cc3cc4OCOc4cc3nc2NC)c2cc(OC)c(OC)cc12

InChI Key InChIKey=QERHNMITJZKQBW-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 187182   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Allergan

US Patent

LigandBDBM187182(US9670181, 61 1-ethyl-6,7-dimethoxy-4-((6-(methyla...)Copy SMILESCopy InChI

Affinity DataIC50: 2.20nMpH: 7.4 T: 2°CAssay Description:The PDE assay is based on the homogenous time-resolved fluorescence resonance energy transfer (TR-FRET) technology (LANCE from Perkin Elmer). This co...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/19/2018
Entry Details
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