BDBM18714 4-{[(4-chlorophenyl)sulfanyl]methyl}-6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinoline::dihydroquinoline compound, 25

SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(CSc3ccc(Cl)cc3)c2c1

InChI Key InChIKey=DKLYGWOPRPJURQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18714   

TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18714(4-{[(4-chlorophenyl)sulfanyl]methyl}-6-(2-methoxyp...)
Affinity DataIC50: 800nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2007
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18714(4-{[(4-chlorophenyl)sulfanyl]methyl}-6-(2-methoxyp...)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2007
Entry Details Article
PubMed