BDBM18687 (2R)-3-{[4-(2-bromoacetamido)phenyl]sulfanyl}-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide::Bicalutamide Analogue, (R)-13

SMILES C[C@](O)(CSc1ccc(NC(=O)CBr)cc1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=JILZNWHOJVTEKH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18687   

TargetAndrogen receptor(Rat)
University of Tennessee At Memphis

LigandPNGBDBM18687((2R)-3-{[4-(2-bromoacetamido)phenyl]sulfanyl}-N-[4...)
Affinity DataKi:  100nM ΔG°:  -8.87kcal/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Tennessee At Memphis

LigandPNGBDBM18687((2R)-3-{[4-(2-bromoacetamido)phenyl]sulfanyl}-N-[4...)
Affinity DataKi:  100nMAssay Description:Inhibition of [3H]mibolerone binding to cytosolic androgen receptor of rat ventral prostateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed