BDBM1867 1-(2-phenylpropyl)-3-1,3-thiazol-2-ylthiourea::N-(1-(2-Phenylpropyl))-N -(2-thiazolyl)thiourea::PETT Analog 33

SMILES CC(CNC(=S)Nc1nccs1)c1ccccc1

InChI Key InChIKey=NQIQJPRBRMXGMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1867   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM1867(N-(1-(2-Phenylpropyl))-N -(2-thiazolyl)thiourea | ...)
Affinity DataIC50: 450nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2004
Entry Details Article
PubMed