BDBM186574 US10787472, Compound 10::US9163042, 10

SMILES Cc1cc(F)ccc1Oc1ccc(cc1C(=O)Nc1ccn(COP(O)(O)=O)c(=O)c1)C(F)(F)F

InChI Key InChIKey=OSCBQHPCUKAFNW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 186574   

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM186574(US9163042, 10 | US10787472, Compound 10)
Affinity DataIC50: 86nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM186574(US9163042, 10 | US10787472, Compound 10)
Affinity DataIC50: 86nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2021
Entry Details
Go to US Patent