BDBM186341 US9163017, 15

SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1nc(c[nH]1)-c1ccc(cc1)C#Cc1ccc(Sc2ccc(N)cc2)c(Nc2ncnc3nc(ccc23)C(C)C)c1

InChI Key InChIKey=JWEJXCFFCQUVGV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 186341   

TargetGenome polyprotein(HCV)
Abbvie

US Patent
LigandPNGBDBM186341(US9163017, 15)
Affinity DataIC50: 55nMAssay Description:The inhibitory effects of the compounds of the invention on HCV replication can be determined by measuring activity of the luciferase reporter gene. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent