BDBM186118 US9163012, 35, Isomer 1::US9163012, 35, Isomer 2

SMILES Cc1ccc(nc1)C1CCN(C1)C(=O)OC1C2CC3CC1CC(C3)(C2)C(N)=O

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 186118   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM186118(US9163012, 35, Isomer 2 | US9163012, 35, Isomer 1)
Affinity DataIC50: 1.61nMT: 2°CAssay Description:Inhibition of microsomal preparations of 11.beta.-HSDl by compounds of the present invention, as described essentially previously (K. Solly, SS Mundt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM186118(US9163012, 35, Isomer 2 | US9163012, 35, Isomer 1)
Affinity DataIC50: 100nMT: 2°CAssay Description:Inhibition of microsomal preparations of 11.beta.-HSDl by compounds of the present invention, as described essentially previously (K. Solly, SS Mundt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent