BDBM18535 6-[ethyl(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one::6-dialkylamino-4-trifluoromethylquinolin-2(1H)-one, 4k

SMILES CCN(CC(F)(F)F)c1ccc2[nH]c(=O)cc(c2c1)C(F)(F)F

InChI Key InChIKey=BMTWPTWVPQCHNC-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18535   

TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM18535(6-[ethyl(2,2,2-trifluoroethyl)amino]-4-(trifluorom...)
Affinity DataKi:  7.10nM ΔG°:  -11.6kcal/mole EC50:  0.400nMpH: 7.4 T: 2°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2007
Entry Details Article
PubMed