BDBM18505 6-{[(5,7-dichloronaphthalen-2-yl)(methyl)amino]methyl}-7-methylpteridine-2,4-diamine::Pteridine compound, 16

SMILES CN(Cc1nc2c(N)nc(N)nc2nc1C)c1ccc2c(Cl)cc(Cl)cc2c1

InChI Key InChIKey=NJAGEILJHVESNB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18505   

TargetDihydrofolate reductase(Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG...)
University of Connecticut At Storrs

LigandPNGBDBM18505(6-{[(5,7-dichloronaphthalen-2-yl)(methyl)amino]met...)
Affinity DataIC50: 1.00E+6nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2007
Entry Details Article
PubMed