BDBM18502 6-{[(6-chloronaphthalen-2-yl)(methyl)amino]methyl}pteridine-2,4-diamine::Pteridine compound, 13

SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc2cc(Cl)ccc2c1

InChI Key InChIKey=XXBVTBSTNLWCGN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18502   

TargetDihydrofolate reductase(Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG...)
University of Connecticut At Storrs

LigandPNGBDBM18502(6-{[(6-chloronaphthalen-2-yl)(methyl)amino]methyl}...)
Affinity DataIC50: 2.26E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2007
Entry Details Article
PubMed