BDBM18485 5-[2-(3,4,5-trimethoxyphenyl)ethynyl]pyrimidine-2,4-diamine::TMP derivative containing acetylenic linker, 7
SMILES COc1cc(cc(OC)c1OC)C#Cc1cnc(N)nc1N
InChI Key InChIKey=HWMMHIATTCGLSZ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 18485
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium parvum)
Dartmouth College
Dartmouth College
Affinity DataIC50: 1.00E+6nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
