BDBM184574 US9155743, 4

SMILES CN[C@@H](C)C(=O)Nc1ccc2NC(=O)C(Cc3ccccc3)Oc2n1

InChI Key InChIKey=JHOGCKICQOYEMB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 184574   

TargetE3 ubiquitin-protein ligase XIAP(Human)
Astex Therapeutics

US Patent
LigandPNGBDBM184574(US9155743, 4)
Affinity DataIC50: 5.50E+3nMpH: 7.5 T: 2°CAssay Description:Modified SMAC peptides and compounds were tested for their ability to displace the fluorescent tracer from either XIAP, cIAP-1 or cIAP-2. BIR3 domain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2016
Entry Details
Go to US Patent

TargetBaculoviral IAP repeat-containing protein 2(Human)
Astex Therapeutics

US Patent
LigandPNGBDBM184574(US9155743, 4)
Affinity DataIC50: 505nMpH: 7.5 T: 2°CAssay Description:Modified SMAC peptides and compounds were tested for their ability to displace the fluorescent tracer from either XIAP, cIAP-1 or cIAP-2. BIR3 domain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2016
Entry Details
Go to US Patent